FACTOR XI DEFICIENCY AND ITS MANAGEMENT Third Edition
نویسندگان
چکیده
منابع مشابه
Factor XI deficiency in Iranians: its clinical manifestations in comparison with those of classic hemophilia.
BACKGROUND AND OBJECTIVES In patients with factor XI(FXI) deficiency the bleeding tendency is poorly correlated with plasma factor levels. The purpose of this study was to evaluate whether or not this discrepancy is also present in a large series of patients from Iran, a previously unexplored ethnic group. DESIGN AND METHODS In 28 FXI - deficient patients bleeding symptoms and their relation ...
متن کاملDominant Factor XI Deficiency Caused by Mutations in the Factor XI Catalytic Domain Running title: Autosomal dominant factor XI deficiency
(2497 articles) Hemostasis, Thrombosis, and Vascular Biology (1597 articles) Free Research Articles (3667 articles) Clinical Trials and Observations Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found ...
متن کاملAnesthetic strategy for cesarean section in a patient with factor XI deficiency. Case report.
BACKGROUND AND OBJECTIVES Factor XI deficiency is a rare hematologic disorder. Hemophilia C (factor XI deficiency) affects both genders and it is usually asymptomatic, manifesting only as postoperative hemorrhage. It is an autosomal recessive, homozygous or heterozygous, disorder, and its severity depends on the levels of factor XI. The objective of this report was to present the anesthetic str...
متن کاملA comparison of murine and human factor XI.
Factor XI is a plasma glycoprotein that is required for contact activation initiated fibrin formation in vitro and for normal hemostasis in vivo. In preparation for developing a mouse model of factor XI deficiency to facilitate investigations into this protease's contributions to coagulation, we cloned the complementary DNA for murine factor XI, expressed the protein in a mammalian expression s...
متن کاملWhen and where is factor XI activated by thrombin?
To the Editor. bound to the clot is protected and is no longer subject to inhibition by the competitive substrate, fibrinogen, and is able to catalyze the feedback to activate factor XI and enhance the intrinsic cascade. The pathway by which factor XI is initially activated is still unclear, because the autoactivation of factor is completely inhibited by fibrinogen and high molecular weight kin...
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